Calendar: 1972-1973 Page 447

Annual Report of the Delegacy lxv adrenoceptors was made use of in trial of sympathomimetics in chronic simple glaucoma Dr Paterson Dr Κ Morton's unit continued investigation on the cellular mode of action of certain auta- coids in particular the prostaglandines and bradykinin The dependence of the contractile effect of these substances on the membrane potential and on the supply of metabolic energy is being studied in visceral smooth muscle preparations Prostaglandin E2 was found to be released from iris smooth muscle during sustained tonic contraction MrJ Posner Another intraocular smooth muscle-the ciliary muscle-was investi- gated by Mrs Alison Boydell for relation with intraocular pressure studies Mrs Hatham Al-Jubouri devised technique for selective examination of the responses to drugs of different vascular beds in the rat Dr Prince continued his investigations into the localisation and activity of choline acetyltransferase in nerve tissue and was joined in these studies by Mrs Elizabeth Coleshill Mr Prempeh and Mr Toates Dr Littleton began work on the biological basis for drug dependence with special reference to alcohol addiction The research programme of the department received generous support from the Science Research Council with grant to Dr Prince for research technician and for equipment Dr Prince also had grant from the John Kemp Fund for print-out equipment and from the Wellcome Trustees for Research Studentship Dr Littleton has also been generously supported over period of three years with grant from the Benescience Foundation for the purchase of equipment and for the support of research technician DEPARTMENT OF PHYSIOLOGY Number of Students 255 58 Sc 16 Departmental Notes The year was marked by considerable development of research pro- jects made possible by financial support from the Medical Research Council and the Wellcome Trust In addition to fairly sophisticated pieces of apparatus funds were made available to establish direct communication between the depart- ment and computer With this apparatus the previously laborious