Calendar: 1961-1962 Page 431

1 ANNUAL REPORT examined Dr Darbre and studies of the intermediate metabolism of carbohydrates as seen in moulds were extended Dr Spencer Professor Robson visited University College Ibadan as University Examiner in Biochemistry He was appointed examiner by Cairo University for postgraduate thesis in Biochemistry department of pharmacology Number of Students 247 Sc Special Physiology Occasional 14 Ph Results of Examinations For Second results see under Department of Anatomy for Sc Special Physiology see under Department of Physiology Departmental Notes Professor Brownlee was University of London examiner at the University College of the West Indies where he also gave three lectures During short visit to the United States he lectured at Cornell Medical Centre at Yeshiva Medical School New York at the National Institute of Health Washington and in Detroit and Morris Plains The research work of the department continued on the mechanism of action of the neuro-humors and on the development of methods to advance this research Professor Brownlee Dr Leach Mr Reiif and Mr Harry observed the effects of central nervous stimulants of diverse chemistry which released or inhibited the release of 5-hydroxytryptamine Dr Leach measured the amounts of 5-hydroxytryptamine released from the isolated guinea-pig ileum by these stimulants and related the amounts to the work done by the ileum Release of acetylcholine by the ileum when stimulated electrically across its wall was estimated on the rat blood pressure preparation by Mr Harry and again related to the work done by the muscle The influence of monamine oxidase inhibitors on the metabolism of 5-hydroxytryptamine was examined by Mr Reiif by paper chromatographic separation of the excretion products of the amine He also made chromatographic analysis of Colimycin new antibiotic drug Dr Paterson's research into contractile processes in muscle was concerned with the relation between the membrane potential and ionic environment of the muscle during contractures induced by drugs The modes of action of sympathomimetic amines and substances affecting their actions were further studied on trachealis muscle by